5-ChloroAcetyl Salicylamide
- Chemical Structure
- Chemical Details
- End Use
- Manufacturing & Quality Control
CAS: 33254-88-5
Chemical Name: 5‑(2‑Chloroacetyl)‑2‑hydroxybenzamide
Molecular Weight: 213.62g/mol
Molecular Formula: C₉H₈ClNO₃
Physical Appearance: Likely white/off-white crystalline powder, less soluble in water
5‑Chloroacetyl-2-hydroxybenzamide (CAS No. 33254-88-5) is a key intermediate in the synthesis of Labetalol, an antihypertensive active pharmaceutical ingredient (API) used to treat high blood pressure and hypertensive crises. The chloroacetyl-functionalized salicylamide structure is crucial in constructing the core framework of adrenergic receptor antagonists, enabling downstream derivatization steps leading to Labetalol synthesis.
Additionally, 5-Chloroacetylsalicylamide is utilized in medicinal chemistry for the development of salicylamide-based analgesics, antipyretics, and as a precursor in synthesizing heterocyclic compounds like benzoxazoles and quinazolines. These derivatives are explored in R&D programs targeting anti-infective, anti-inflammatory, and anticancer therapies.
Our 5-ChloroAcetyl Salicylamide is manufactured under strict GMP conditions, ensuring the highest quality standards. The product undergoes rigorous quality control testing for identity, potency, purity, and safety before release.