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Products – 2,4,5,6-Tetraaminopyrimidine sulfate – Methotrexate and Pralatrexate Intermediates

2,4,5,6-Tetraaminopyrimidine sulfate

  • Chemical Structure
  • Chemical Details
  • End Use
  • Manufacturing & Quality Control

CAS: 5392-28-9

Chemical Name: Pyrimidine‑2,4,5,6‑tetramine; sulfuric acid

Molecular Weight: 238.22g/mol

Molecular Formula: C₄H₁₀N₆O₄S (1:1 sulfate)

Physical Appearance:  Crystalline powder ranging from ochre to brown in color


 

2,4,5,6-Tetraaminopyrimidine sulfate (TAPS) is a vital chemical intermediate prominently utilized in pharmaceutical synthesis, particularly in the production of the antineoplastic agent Methotrexate. Its tetraaminopyrimidine core is essential in building folate analog structures crucial for antimetabolic cancer therapies Thermo Fisher Scientific.

Moreover, TAPS serves as a key developer component in oxidative hair dye formulations, where it reacts with color couplers (upon oxidation) to produce permanent hair colors European Commission+3European Commission+3PubMed+3. Its dual applications in pharmaceutical manufacturing and cosmetic chemistry underscore its versatility across industries.

Our 2,4,5,6-Tetraaminopyrimidine sulfate  is manufactured under strict GMP conditions, ensuring the highest quality standards. The product undergoes rigorous quality control testing for identity, potency, purity, and safety before release.

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